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2-Tetrahydrofuroic acid CAS 16874-33-2

  • Pharmaceutical intermediates...
CAS : 16874-33-2
Molecular : C5H8O3
EINECS : 605-530-1

Detailed introduction



2-Tetrahydrofuroic acid Description

Chemical Name: 2-Tetrahydrofuroic acid

Synonyms: Tetrahydro-2-furoic Acid; T2F; THFC; THFAC

Appearance: Colorless to light yellow liquid

Assay: 99%

2-Tetrahydrofuroic acid Typical Properties

Melting point21°C
Boiling point128-129°C 13 mm Hg(lit.)
Density1.209g/mL at 25 °C(lit.)
Water Solubilitysoluble
AppearanceLiquid
ColorTransparent yellow to brown
Refractive indexn20/D 1.46 (lit.)

2-Tetrahydrofuroic acid Usage

Core Function: An oxygen-containing heterocyclic fatty acid, structurally a saturated furan derivative. It is a highly reactive chiral/chiral pharmaceutical and flavor intermediate.


Application Areas:

Pharmaceutical Synthesis (Core Application): Used in the synthesis of antitumor drugs and lead compounds.

  • As a side-chain introducer, it is widely used in the molecular construction of novel total synthetic antibiotics, antiviral drugs, and cardiovascular drugs.

  • Specific derivative salts are used as substrates for metabolic enzyme reactions in biomedical research.

Fragrances and Flavors: Its ester derivatives possess unique fruity, nutty, and herbal aromas, making it an important blending ingredient in high-end food and tobacco flavorings.

Agricultural Chemicals: Used in the development and synthesis of highly selective fungicides and plant growth regulators.

2-Tetrahydrofuroic acid Packaging and Shipping

200kg/drum

2-Tetrahydrofuroic acid Storage

It should be stored in a clean, dry and cool place, preventing from sunlight, rain.


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