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Common Name: BF₃·Et₂O
CAS Number: 109-63-7
Molecular Type: Lewis acid catalyst / Organic synthesis reagent
Boron trifluoride diethyl etherate (CAS 109-63-7) is a stable complex formed from boron trifluoride and anhydrous diethyl ether. It is one of the most commonly used and important Lewis acid catalysts in organic synthesis. Compared to gaseous BF₃, this product offers advantages such as greater safety, easier handling, and higher catalytic efficiency.
BF₃·Et₂O is widely used in the synthesis of pharmaceutical intermediates, fragrances and flavors, resin polymerization, olefin reactions, esterification, and condensation reactions, and is a core reagent in the fine chemical and pharmaceutical industries.
| Item | Specification |
|---|---|
| Product Name | Boron Trifluoride Etherate |
| CAS Number | 109-63-7 |
| Molecular Formula | C4H10BF3O |
| Molecular Weight | 141.93 g/mol |
| Appearance | Colorless to pale yellow liquid |
| Odor | Ether-like |
| Density (20°C) | ~1.12 g/cm³ |
| Boiling Point | ~126°C |
| Solubility | Reacts with water |
| BF₃ Content | ≥47.8% |
| Ether Content | Balance |
| Shelf Life | 12 months |
1. Pharmaceuticals and Pharmaceutical Intermediates
Used as a highly efficient catalyst for condensation, cyclization, and acylation reactions.
Widely used in the synthesis of antibiotics, vitamins, and hormone intermediates.
2. Flavors and Fine Chemicals
Used in the synthesis of aromatic compounds such as vanillin and ethyl vanillin.
Improves reaction selectivity and yield.
3. Resin and Polymer Industry
Used as a polymerization initiator or catalyst.
Applied in phenolic resin and epoxy resin systems.
4. Organic Synthesis and Laboratory Reagents
Friedel–Crafts reaction
Esterification, alkylation, and isomerization reactions
✅ High purity and strong catalytic activity
✅ Safer and easier to handle compared to gaseous BF₃
✅ Good reaction selectivity and fewer side reactions
✅ Available in industrial and reagent grades
✅ Stable batch quality, suitable for continuous production
🌍 Years of experience in exporting organic catalysts
🏆 Strict quality control and compliance management for hazardous chemicals
📄 We provide COA / MSDS / TDS / Dangerous Goods Certificate
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Packaging Specifications: 25kg / 50kg galvanized steel drums
Transportation Method: Transportation of hazardous chemicals
Storage Conditions: Sealed, protected from light, dry, and away from water sources
Precautions: Avoid direct contact with water and alcohols.
Q1: Is Boron Trifluoride Etherate dangerous?
A: It is corrosive and moisture-sensitive; proper handling is required.
Q2: Can it replace gaseous BF₃?
A: Yes, BF₃ etherate is widely used as a safer alternative.
Q3: What applications is it mainly used for?
A: Pharmaceutical intermediates, resins, fragrances, and organic synthesis.
Q4: Do you provide COA and MSDS?
A: Yes, full technical documentation is available.
Q5: Is custom packing available?
A: Yes, customized packaging can be arranged.
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