CAS number：70-18-8
molecular formula：C10H17N3O6S
molecular weight：307.32
EINECS number：200-725-4

English synonyms

glutatiol;glutatione;glutide;glutinal;isethion;l-glutatione;N(N-L-.gamma.-Glutamyl-L-cysteinyl)glycine;n-(n-l-gamma-glutamyl-l-cysteinyl)-glycin

Related categories

Peptides; chemical raw materials; biochemical reagents; standard products; specialty drugs; glutathione; antidotes; bulk drugs; amino acids and derivatives; other biochemical reagents; antitumor; plant extracts; raw materials; small molecule inhibitors; small Molecular inhibitors, natural products; biochemistry; amino acid derivatives; food additives; pharmaceutical raw materials; amino acids; plant biochemical extracts; extracts; vitamins; pharmaceutical chemical raw materials; amino acids and their derivatives; Chinese medicine reference substances; medicine raw materials; nutritional research; amino acids; reference substances; cosmetic raw materials - whitening agents; chemical reagents; reference substances - impurity reference substances; nutrition fortifiers; hair growth shampoo series; cosmetic raw materials - whitening and freckle removal raw materials; food additives; Amino acids; standard analytical reagents; coenzyme ribonucleoside nucleic acid series; intermediates; health products; cell biology - cellular oxidative stress; health products raw materials - cosmetic raw materials; nutritional fortifiers; food additives; biological and chemical drugs - drugs Impurities;Technical Medicines;Chemicals;Additives;Medical Raw Materials;Reduced Glutathione;Reference Substances-Traditional Chinese Medicine Reference Substances;Cosmetic Raw Materials;alkaloids;Standards-Traditional Chinese Medicine Standard Products;pharmacetical;Amino Acids 13C, 2H, 15N; Antioxidant;Biochemistry;Amino Acids & Derivatives;Intermediates & Fine Chemicals;Pharmaceuticals;Material;Pharmaceutical intermediates;Inhibitors;pharmaceutical;chemical; body; off-the-shelf; pharmaceutical peptides; other; organic chemical raw materials; high-purity biochemical reagents; content products; beauty peptides; key products; kits-cell analysis kits; intermediates-organic intermediates; reagents; general biochemical reagents-amino acids ;Kit-Elisa kit;whitening series;kit-biochemical kit;70-18-8;scientific research materials;beauty peptides;catalysts;whitening;biological buffer series;cosmetic raw materials;spot;chemical reagents

Introduction

Glutathione (GSH) is a tripeptide compound formed by the condensation of glutamic acid, cysteine and glycine through peptide bonds, and its chemical name is γ-L-glutamyl-L-cysteinyl- Glycine, its structural formula is shown in Figure 1. As can be seen from the structural formula in the figure, GSH is different from other peptides and proteins. It has a special peptide bond in its molecule, which is composed of the γ-carboxyl group (—COOH) of glutamic acid and the α-amino group of cysteine—(— NH2) condensed peptide bonds.

Chemical properties

Use

Reduced glutathione is a small-molecule peptide that exists in large quantities in living organisms, especially in liver cells. It can protect liver cell membranes, promote liver enzyme activity, and combine with many toxic chemicals to detoxify. effect. It has a good curative effect on liver injury, liver cirrhosis and other diseases caused by drug poisoning, alcoholism and other reasons.

It has the functions of anti-oxidation, scavenging free radicals, detoxification, enhancing immunity, anti-aging, anti-cancer, and anti-radiation hazard.

Uses: Biochemical reagents, antidote, mainly used for poisoning of heavy metals, acrylonitrile, fluoride, carbon monoxide and organic solvents

Biochemical research

An endogenous antioxidant that plays an important role in the reduction of reactive oxygen species formed during cellular metabolism and burst respiration. Glutathione-S-transferases catalyze the formation of glutathione thioethers with xenobiotics, leukotrienes, and other molecules with electrophilic centers. Glutathione also forms disulfide bonds with cysteine residues in proteins. Through these mechanisms, it may have the miraculous effect of reducing the efficacy of anticancer agents.