CAS number：84380-01-8
molecular formula：C12H16O7
molecular weight：272.25
EINECS number：209-795-0

English synonyms

Alpha Arbutin Powder;4-hydroquinone-alpha-d-glucopyranoside;alpha-arbutin;a-Arbutin;Hydroquinone O-α-D-Glucopyranoside;4-Hydroxyphenyl a-D-glucopyranoside;(2R,3S,4S,5R,6S)-2-(HYDROXYMETHYL)-6-(4-HYDROXYPHENOXY)TETRAHYDROPYRAN-3,4,5-TRIOL;4-hydroxyphenyl alpha-D-glucopyranoside

Related categories

Plant extracts; superior products; cosmetic raw materials; compounds; standard Chinese medicines; whitening efficacy of cosmetic raw materials; standard products; pharmaceutical raw materials; raw materials; additives; cosmetic raw materials-whitening agents; plant component monomers; self-produced raw materials; chemical raw materials; Intermediates; Cosmetic Daily Chemical Raw Materials; Standard Substances-Reference Substances; Chemical Raw Materials-1; Other Raw Materials; Standard Products; Medical Raw Materials- Raw Materials; Raw Materials; α-Arbutin; Chemicals;Plant extract;Aromatics;Carbohydrates & Derivatives;Intermediates & Fine Chemicals;Pharmaceuticals;reference substance-Chinese medicine reference substance;chemical raw material;reference substance;daily chemical;pharmaceutical,pesticide and dye intermediate;standard substance,reference substance;daily chemical raw material;high content monomer;traditional Chinese medicine reference Products; organic intermediates; organic chemical raw materials; biological products; inorganic salts; whitening and freckle-removing raw materials; fine chemical raw materials; content products; cosmetic functional raw materials additives - arbutin; daily chemicals; whitening series; raw materials intermediates; 84380-01 -8; biochemical industry; organic raw materials; chemical reagents

Introduction

Arbutin is a hydroquinone glycoside compound, the chemical name is 4-hydroxyphenyl-D-glucopyranoside (4-Hydroquinone-alpha-D-glucopyranoside), which exists in bearberry, bilberry and other plants. It is a new non-irritating, non-allergic and highly compatible natural whitening active substance. There are two structural and functional functional groups in the molecular structure of arbutin: one is a glucose residue; the other is a phenolic hydroxyl group. The physical state of α-arbutin is white to light gray powder, which is easily soluble in water and ethanol.

Chemical properties

White needle-like crystals, soluble in methanol, ethanol, DMSO and other organic solvents, derived from bearberry leaves, rock cabbage.

Use

●  α-Arbutin has a good therapeutic effect on scars caused by ultraviolet burns, and has good anti-inflammatory, repairing and whitening effects. Can inhibit the production and deposition of melanin, remove pigmentation and freckles.

●  Alpha-arbutin is a chemical, similar to arbutin, that inhibits the production and deposition of melanin, and removes pigmentation and freckles. Studies have shown that -arbutin can inhibit the activity of tyrosinase at a relatively low concentration, and its inhibitory effect on tyrosinase is better than that of arbutin. Alpha-arbutin can be used in cosmetics as a whitening agent.

●  α-Arbutin can inhibit the activity of tyrosinase at a relatively low concentration, and its inhibitory effect on tyrosinase is better than that of arbutin

●  The whitening mechanism of α-arbutin directly inhibits tyrosinase activity, thereby reducing melanin production, rather than reducing melanin production by inhibiting cell growth or tyrosinase gene expression. Since α-arbutin is a more efficient and safer whitening active substance, many cosmetic companies at home and abroad have used α-arbutin instead of β-arbutin as a whitening additive.

Production method

●  The samples obtained by the reaction were first extracted with ethyl acetate, then extracted with n-butanol, evaporated to dryness by a rotary evaporator, and then centrifuged. The supernatant was analyzed by HPLC and compared with α-arbutin standard Compare the HPLC chromatogram of the product, compare whether the sample and α-arbutin have the same retention time, and preliminarily infer whether the sample contains α-arbutin. The product after extraction and purification was identified by the positive ion mode of LC-ESI-MS/MS. By comparing the relative molecular mass of α-arbutin product with the relative molecular weight of α-arbutin standard, it can be determined whether the product is α-arbutin.