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      Ectoine CAS 96702-03-3

      • Ectoine CAS 96702-03-3...
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      Detailed introduction



      CAS number:96702-03-3
      molecular formula:C6H10N2O2
      molecular weight:142.16
      EINECS number:431-910-1

      English synonyms

      ECTOIN;(S)-2-METHYL-1,4,5,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID;THP[B];ECTOINE;2-METHYL-1,4,5,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID;(S)-1,4,5,6-Tetrahydro-2-methyl-4-pyrimidincarbonsure;ECTOINE BIOCHEMIKA 99%;Ectoine sodium salt monohydrate

      Related categories

      Other biochemical reagents; Chinese medicine reference substances; chemical raw materials-1; health product raw materials; cosmetic raw materials; functional substances-tetrahydropyrimidine; organic chemical raw materials; medical raw materials; Halogenated Hydrocarbons, Isobenzofuran; adhesives; biochemical reagents; Medical polymer materials; chemical intermediates; pharmaceutical raw materials; chemical intermediates; raw materials; alkaloids; other raw materials; chemical raw materials; ectoine tetrahydromethylpyrimidine carboxylic acid; biological products; chemical raw materials; plant extracts ;Content Products;CARBOXYLICACID;Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;API;Chemical Reagents;1;Cosmetic Functional Raw Material Additives-Ecodotine;Daily Chemicals;APIs and Intermediates;Bulk;Natural High-content monomer; raw material intermediates; anti-aging; biochemical industry; fine chemical raw materials; 96702-03-3; daily chemical and cosmetic active molecules; chemicals; ectoine; Jarpro; scientific research materials; organic raw materials; spot

      Introduction

      Ectoine is also called tetrahydromethylpyrimidine carboxylic acid. It has two major functions: 1) Moisturizing: It is an important substance to maintain osmotic pressure balance, and its unique molecular structure has a strong ability to complex water molecules, which can make intracellular The free water is structured and is an excellent natural moisturizer. 2) Repair: ectoine can resist the damage of ultraviolet rays to the skin and repair the cell DNA damage caused by ultraviolet rays.

      Chemical properties

      Melting point

      ~280°

      Boiling point

      381.5±35.0 °C(Predicted)

      Specific optical rotation

      D20 +140° (c = 1.0 in methanol)

      Density

      1.37

      Storage conditions

      2-8°C

      Solubility

      methanol: 20 mg/mL, clear, colorless

      Shape

      Solid

      Acidity coefficient(pKa)

      3.14±0.20(Predicted)

      Color

      White to Off-White

      BRN 

      7288977

      Stability

      Hygroscopic

      InChIKey

      WQXNXVUDBPYKBA-YFKPBYRVSA-N

      Use

      ●  Ectoine is a natural and effective cosmetic active ingredient. Due to its wide range of cell protection functions, it can be used in many cosmetic products with different functions. Ectoine has the functions of moisturizing, anti-oxidation, protection against photoaging, and sun protection.
      good moisturizing
      Pretreating the skin with Ectoine can reduce skin damage caused by dehydration; one molecule of Ectoine can complex four or five water molecules to structure the free water in cells. Compared to glycerin, ectoine is more moisturizing to the skin.
      Relevant data show that during the application period of Ectoine, the skin's water-holding capacity can continue to improve, and the skin's water-holding capacity will not drop immediately after discontinuation. The skin's water-holding capacity is still higher than that of the control group after one week of discontinuation.
      Antioxidant effect
      Clinical trials have shown that ectoine can prevent the weakening of the antioxidant capacity of cells with the increase of age, and has a certain antioxidant capacity.
      The experimental data show that the mixed use of 0.1 mM Ectoine, 0.5 mM methionine and 1.5 mM mannitol can reduce the DNA single-strand break of human glial cells under the light source of 400-800 nm, and reduce the intensity of ROS oxidation reaction, thereby reducing the oxidation of light to the skin harm.
      immune system protection
      Langerhans cells in the epidermis play a key role in the skin's immune system, but are very sensitive to UV stress. And Ectoine just keeps the number of Langerhans cells from being reduced by ultraviolet radiation, so that the skin's immune system maintains normal functioning.
      Protection against photoaging and sun protection
      Skin aging is not only the result of the passage of time, one of the important external factors is ultraviolet rays, especially UVA (320-400nm).
      In the entire ultraviolet band, UVA has the longest wavelength and the lowest energy, but unlike UVB, the change of UVA content in sunlight is little affected by latitude, time period, weather and season, so the daily and annual UVA exposure The doses are almost fixed and build up in large quantities over our lifetimes.

      ●  With its moisturizing and repairing properties, ectoine is widely used in skin care products and can be used to improve skin tone.


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