CAS number：101-41-7
molecular formula：C9H10O2
molecular weight：150.17
EINECS number：202-940-9

English synonyms

Acetic acid, phenyl-, methyl ester;METHYL ALPHA-TOLUATE;METHYL BENZYLFORMATE;METHYL A-TOLUATE;METHYL PHENYLACETATE;FEMA 2733;Methyl phenylacetate/Phenylacetic acid methyl ester;Phenylacetic Acid Phenylacetate

Related categories

Food Additives; Edible Flavourings (Flavoring Agents); Natural Equivalent Flavourings and Artificial Fragrances; Aromatic Hydrocarbons; Organic Raw Materials; Flavors and Fragrances; General Reagents; Esters; Intermediates; Cosmetic Raw Materials; Organics;APIintermediates;AlphabeticalListings;FlavorsandFragrances;M-N;C8toC9;CarbonylCompounds ;Esters;flavoring;PharmaceuticalIntermediates;organic chemicals;organic chemical raw materials;food additives;daily chemical raw materials;chemical raw materials;synthetic fragrances;high quality and low price;liquid

Introduction

Methyl phenylacetate is used in edible flavor formulations to prepare honey, chocolate, tobacco and other flavors; it can also be used in daily chemical flavors to prepare rose, oriental flavors and other flavors. IFRA has no restrictions.

Colorless liquid. Aroma: Strong, sweet, delicate honey-like aroma. Relative density (water=1): 1.061-1.069. Solubility: miscible with ethanol and ether, soluble in acetone, insoluble in water.

●  Used as a spice, for the preparation of honey, chocolate, tobacco and other flavors

●  Methyl phenylacetate is used as a reagent in the synthesis of various organic reactions, one of which is the synthesis of methyl occipate; a lichen metabolite with anti-inflammatory properties.

●  Methyl phenylacetate has a honey-like sweetness and a slight musk aroma. It is often used in the preparation of floral fragrances, such as rose, briar and other fragrances, and used in tobacco and soap. The product is also used in organic synthesis and the manufacture of drugs atropine and anisodamine (synthetic method).

●  It is derived from phenylacetonitrile by hydrolysis and esterification. Put methanol into a dry glass-lined reaction pot, stir and cool to below 30°C, add sulfuric acid dropwise, heat up to 90°C after adding, and start adding phenylacetonitrile dropwise, control the temperature at about 95°C, and finish adding in 1.5h. After reacting at 95-100°C for 6 hours, it was cooled to below 40°C and diluted with water equivalent to about 0.6 times of the reaction solution. The acid water was separated by standing, and a saturated sodium carbonate solution was added for neutralization and washing, and the aqueous layer was discarded. It is dehydrated with anhydrous calcium chloride and fractionated under reduced pressure to obtain methyl phenylacetate with a yield of 80%. Another preparation method is to pass benzyl chloride, anhydrous methanol and water to saturation with hydrogen chloride under reflux, place for 2-3h, and heat for 1h to generate this product.

●  By phenylacetic acid or phenylacetonitrile methyl esterification.