Acetone oxime CAS 127-06-0

CAS number：127-06-0
molecular formula：C3H7NO
molecular weight：73.09
EINECS number：204-820-1

English synonyms

N-Isopropylidenehydroxylamine;N-Propan-2-ylidenehydroxylamine;propan-2-oneoxime;DI METHYL KETOXIME;LABOTEST-BB LT00516122;ACETOXIME;ACETONE OXIME;2-PROPANONE OXIME

Related categories

Synthetic material intermediates; biochemical reagents; medical raw materials; general reagents; oximes; organic building blocks; carbonyl compounds; other biochemical reagents; , raw materials for dyes and silicone coupling agents, and can also be used for analytical reagents to identify nickel, cobalt, etc.; Pharmaceutical Intermediates; OximinoSilanes; NitrogenCompounds; Intermediates; Inorganic acids; Pharmaceutical, pesticide and dye intermediates; Chemical raw materials; Synthetic intermediates; Main products; Organic chemical raw materials; Chemical materials; Other raw materials; Pharmaceutical raw materials; Ketones; Raw materials; Organic Building Blocks; Oximes

Introduction

Acetone oxime (DMKO for short) is also known as dimethyl ketone oxime. It is white flaky crystal at room temperature, relative density: 0.9113, melting point: 60°C, flash point: 47.2°C, boiling point: 134.8°C, toxicity LD50: 5500mg/kg , Soluble in water, alcohol, ether and other solvents, the saturated solubility of aqueous solution is 25% (mass percentage), its water solubility is neutral, it is easy to hydrolyze in dilute acid, and it can make potassium permanganate fade at room temperature.

White needle crystal. Melting point 61°C, boiling point 136°C, 134.8°C (97.1kPa), 61°C (2.67kPa), relative density 0.9113 (62/4°C) and refractive index 1.4156. Soluble in water, ethanol, ether and acetone, soluble in acid and alkali, easily hydrolyzed in dilute acid. It evaporates quickly in the air.

●  The product is used in organic synthesis. as an analytical reagent. For the determination of cobalt.

●  It is the raw material of pharmaceuticals, pesticides, dyes and silicone coupling agents, and can also be used for analytical reagents to identify nickel, cobalt, etc.

●  The intermediates of caffeine, theophylline, and SMD are used as reagents for testing cobalt, organic synthesis, new boiler water oxygen scavenger, pharmaceutical and pesticide intermediates, etc.

●  By the reaction of acetone and hydroxylamine hydrochloride. The hydroxylamine hydrochloride solution is slowly added dropwise into acetone, and the reaction temperature is controlled at 40-50°C. Neutralize the oximated reaction solution with 40% sodium hydroxide until alkaline (pH7-8), cool and filter, add the filtered crude product to zeolite, distill at normal pressure, and cool to obtain the crystallized product.