(3-dimethylaminopropyl)ethyl-carbodiimidmonohydrochloride;3-propanediamine,n’-(ethylcarbonimidoyl)-n,n-dimethyl-monohydrochloride;1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydroc;AT test ,only COA;EDC.HCI;N'-(Ethylkohlenstoffimidoyl)-N,N-dimethylpropan-1,3-diaminmonohydrochlorid;Avanafil Impurity 40;Diquafosol Impurity m
Nitrogen compounds; intermediates; aminosilane; proteomics; condensation reagents; biochemical reagents; peptide bond condensation agents; catalysts; condensation agents; pharmaceutical intermediates; protein structure analysis; protected amino acids; pharmaceutical raw materials; fluorine chemistry; peptide synthesis reagents; Polypeptide condensation reaction; synthetic material intermediate; pharmaceutical dehydrating agent; protein heterobifunctional cross-linking reagent; polypeptide reagent; other biochemical reagents; chemical intermediates; biochemical reagents-other chemical reagents; organic chemical raw materials; straight chain compounds; Peptide Coupling Reagents;Biochemistry;Condensation & Active Esterification;Coupling Reactions (Peptide Synthesis);Peptide Synthesis;Reagents for Oligosaccharide Synthesis;Synthetic Organic Chemistry;Peptide;Amine;heteroXlink;EDC; Diagnosis; food additives; chemical reagents; raw materials; basic raw materials; intermediate raw materials; biochemical industry; intermediates-organic intermediates; other raw materials; organic chemistry; chemical raw materials; Chemical intermediates; reagents; medical; peptides; Zero-Length Crosslinker
1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride, referred to as EDC hydrochloride, molecular formula: C8H17N3·HCl, relative molecular weight 191.70, white crystalline powder, easy to absorb moisture , Solubility in water >20g/100ml, soluble in ethanol, melting point 110-114°C, used as an activating reagent for carboxyl groups in amide synthesis, also used for activating phosphate groups, cross-linking of proteins and nucleic acids and immunoconjugates make. The pH range when used is 4.0-6.0, and it is often used together with N-hydroxysuccinimide (NHS) or N-hydroxysulfosuccinimide to improve coupling efficiency.
Chemical properties
| Melting point | 110-115 °C(lit.) |
| Density | 0.877 g/mL at 20 °C(lit.) |
| Vapor Pressure | 0.002Pa at 20℃ |
| Refractive index | n20/D 1.461 |
| Storage conditions | -20°C |
| Solubility | H2O: soluble1 gm/10 ml, clear to very slightly hazy, colorless to very faintly yellow |
| Shape | Crystalline Powder |
| Color | White to off-white |
| Water solubility | Soluble |
| Sensitive | Hygroscopic |
BRN | 5764110 |
| Stability | Stable, but sensitive to moisture. Incompatible with strong acids, strong oxidizing agents, moisture. |
InChIKey | FPQQSJJWHUJYPU-UHFFFAOYSA-N |
LogP | -2.98 at 25℃ |
| CAS database | 25952-53-8(CAS DataBase Reference) |
● Protein and nucleic acid cross-linking reagents, water-soluble carbodiimide-type condensing agents for rapid peptide condensation reactions. The molecule of EDC (or EDAC) has a linear structure, which is used for the condensation reaction of carboxyl groups and primary amines, and has been widely used.
● It is used as a polypeptide condensation agent and cross-linking agent. This product is a water-soluble carbodiimide, which is mainly used as a dehydrating agent in the synthesis of polypeptides, proteins, and nucleotides. It is a water-soluble carbodiimide type that can realize rapid polypeptide condensation reactions. Condensing agent.
● Water-soluble concentrated reagent; general carbonyl activating reagent, used in the process of amide and secondary amine bonding; can react with phosphate groups; used for peptide synthesis; protein and nucleic acid cross-linking; preparation such as immunoconjugates, typically Under conditions, pH 4.0-6.0 and no buffer, under special conditions, the use of amine and carboxylate buffers must be avoided; water-soluble peptide coupling agent; used for carbonyl modification in proteins; used for ester synthesis
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