CAS number：129499-78-1
molecular formula：C12H18O11
molecular weight：338.26
EINECS number：425-980-0
Ascofresh;L-Ascorbic acid, 2-O-.alpha.-D-glucopyranosyl-;AA-2G;ascorbic acid 2-O-glucoside;ASCORBYL GLUCOSIDE, ASCORBIC ACID-2- GLUCOSIDE;2-O-A-D-GLUCOPYRANOSYL-L-ASCORBIC ACID;L-Ascorbic acid 2-o-alpha-glucoside;Pyrido(1,2-A)indol-6(7H)-one, 8,9-dihydro-7-(hydroxy(5-methyl-1H-imidazol-4-yl)methyl)-10-propyl-, (R*,S*)-
Inhibition of melanin in daily chemical cosmetics; anti-oxidation; organic raw materials; polysaccharides; extracts; pharmaceutical raw materials; cosmetics; cosmetic daily chemical raw materials; skin care raw materials; cosmetic additives; cosmetic raw materials-whitening agent; Intermediates; cosmetic raw materials; raw materials; other raw materials; pharmaceutical excipients; vitamin C glucoside (AA2G); chemical industry; API API; medical raw materials; chemical raw materials; raw materials; daily chemicals; daily chemical raw materials; daily chemical products Raw materials; Chinese medicine reference substances; organic intermediates; biological products; content products; organic chemicals; food additives; functional raw material additives for cosmetics-AA2G; whitening series; biological chemicals; chemicals; chemical reagents
Ascorbyl glucoside, also known as VC glucoside, scientific name O-a-D-glucopyranosyl-L-ascorbic acid (2-O-a-D-glucopyranosyl-L-ascorbic acid, abbreviated as AA-2G), is a derivative of VC. The mass is 338.27, and the melting point is 158.5-159.5°C. Because VC has the disadvantages of poor stability and easy oxidation, a substitute product of VC, ascorbyl glucoside, is derived, which can replace VC as a sour agent, reducing agent, antioxidant, bleaching agent and stabilizer, and is widely used in cosmetics, food and medicine and other fields.
| Melting point | 158-163℃ |
| Boiling point | 785.6±60.0 °C(Predicted) |
| Density | 1.83±0.1 g/cm3(Predicted) |
| Vapor Pressure | 0Pa at 25℃ |
| Storage conditions | Keep in dark place,Sealed in dry,Room Temperature |
| Solubility | DMSO (Slightly), Methanol (Slightly) |
| Acidity coefficient(pKa) | 3.38±0.10(Predicted) |
| Shape | Powder |
| Color | White to Off-white |
| Water solubility | Soluble in water. (879 g/L) at 25°C. |
| Maximum wavelength(λmax) | 260nm(H2O)(lit.) |
InChIKey | MLSJBGYKDYSOAE-DCWMUDTNSA-N |
LogP | -2 at 20℃ |
| Surface Tension | 71mN/m at 1g/L and 20℃ |
● 1. Brighten skin tone and inhibit melanin formation After ascorbic acid glucoside is converted into vitamin C and enters skin cells, it can significantly reduce the formation of melanin by inhibiting the activity of tyrosinase. Inhibition of tyrosinase reduces dopaquinone, an intermediate in the synthesis of melanin. Another added benefit is that it converts dopaquinone into levodopa at the same time, which relieves the melanin that has formed, thereby reducing skin pigmentation.
2. Resist UV damage and inhibit the damage to cells caused by ultraviolet radiation. After ascorbyl glucoside is converted into vitamin C, it can greatly reduce the free radicals generated by ultraviolet radiation on the skin, significantly reduce skin damage, and play a role in protecting the skin in sunscreen products. .
● Ascorbyl glucoside is one of the whitening additives announced and approved by the Department of Health, and it is recognized as the most stable vitamin C derivative. At the same time, it is also the most commonly used whitening ingredient in major brands. For example, L'Oreal uses C-glycoside derivatives in synergy with other components to prevent or treat signs of aging on the body or facial skin. Ascorbyl glucoside not only has a good whitening effect, but also has stable chemical properties and is non-irritating to the skin. It is widely used in cosmetics at home and abroad, and has been recognized by the public. The following table lists the common vitamin C derivatives in cosmetics. Application situation.
● A production method of ascorbyl glucoside, characterized in that, comprising the steps of:
Step 1: The ascorbyl glucoside reaction solution is separated by nanofiltration, and the residual VC in the reaction solution is removed to obtain a nanofiltration concentrate;
Step 2: Separating the concentrated nanofiltration solution through a continuous fluid separation device to remove the glucose in the VC glucoside reaction solution;
Step 3: The VC glucoside solution coming out of the continuous fluid separation device is first passed through a positive resin to adjust the pH, and then concentrated through a nanofiltration membrane to remove inorganic salts in the reaction solution to obtain a concentrated VC glucoside solution;
Step 4: Concentrate the VC glucoside concentrate by vacuum distillation, further increase the concentration of VC glucoside, and then crystallize to obtain VC glucoside.
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