CAS number：9004-32-4
molecular formula：C6H7O2(OH)2CH2COONa
molecular weight：
EINECS number：618-378-6

English synonyms

Aquacide I, Calbiochem;Aquacide II, Calbiochem;Carboxyl Methyl Cellulose sodium;Cellex;Cellulose carboxymethyl ether, sodium;cellulose gum;SODIUM CARBOXY METHYL CELLULOSE (CMC);SCMC(SODIUM CARBOXY METHYL CELULLOSE

Related categories

Carbohydrates; fine chemicals; biochemical reagents; other scientific research raw materials; pharmaceutical raw materials; inorganic salts; chemical additives; oilfield chemicals; petroleum drilling chemicals; food additives; thickeners; drilling chemicals; papermaking process Chemicals; Paper Chemicals; Thickeners and Gelling Agents; Professional Reagents; Organic Chemistry; Life Sciences; Excipients; Pharmaceutical Excipients; Biological Sciences; Chemical Reagents; Chemical Products - Organic Chemicals; Biochemical Reagents - Separation Materials and Consumables ; Mud Drilling Chemicals; Food additives; Cellulose; Materials Science; Natural Polymers; Polymer Science; Polymers; thickener; Cellulose; , pesticides and dye intermediates; chemical materials; chemical raw materials; organic chemical raw materials; raw materials; fine chemical raw materials; all products; medical raw materials; bulk goods; food thickeners; chemical reagents; feed additives;

Introduction

Sodium carboxyme thyl cellulose (CMC) is a carboxymethylated derivative of cellulose, also known as cellulose gum, which belongs to anionic cellulose ether and is the most important ionic cellulose gum. It is usually an anionic polymer compound prepared by reacting natural cellulose with caustic alkali and monochloroacetic acid. The molecular weight of the compound varies from several thousand to one million.

Chemical properties

Use

●  As emulsion stabilizer and thickener. my country stipulates that it can be used for instant noodles, with a maximum usage of 5g/kg; in beverages (excluding solid beverages), the maximum usage is 1.2g/kg; in biscuits, puffed foods, popsicles, ice cream, pastries and jellies, it can be used in moderation according to production needs .

●  Thickener, stabilizer; Texture improver; Gelling agent; Non-nutritive leavening agent; Moisture migration control agent; Foam stabilizer; Reduce fat adsorption.
Because of its viscosity, stability, protective colloid, and film forming properties, it is used in ice cream to improve water retention and tissue structure (0.3% to 0.5%). But it needs to be used in combination with sodium alginate, etc.
Used in instant noodles to make the product uniform, improve the structure, easy to control moisture, and easy to operate.
Adding it to jam, butter, peanut butter, etc. can improve spreadability. The dosage for jam and seasoning sauce is 0.5% to 1%.
Adding 0.1% wheat to bread, cakes, etc. can prevent water evaporation and aging.
It is still used as a solid agent for powdered oil, spices, etc., and its dosage is 20% to 60% (mixed with oil, spices, etc. in CMC aqueous solution, fully emulsified, dried, and pulverized).
Foam stabilizer for beer.
Fruits and vegetables, eggs, etc. are covered with 2% to 3% CMC solution containing parabens and dried to maintain flavor and prevent mildew. After absorbing water, it has strong expansibility and is indigestible. It can be used as a diet food for biscuits.

●  Widely used as thickener, suspending agent, binder, protective colloid, etc. in the pharmaceutical, daily chemical, and food industries

●  For oil drilling, textile printing and dyeing

●  For oil and gas drilling mud stabilizer, textile slurry, paper strengthening agent, adhesive, etc.

●  Used in combined washing, cigarettes, construction, daily chemicals

●  For textile sizing, drilling, etc.

●  It is used as fluid loss reducer for water-based drilling fluid and has a certain viscosity-increasing effect.

●  It can be used as a reinforcing agent in the pulp, also used for surface sizing, and used as a viscosity regulator when coating processed paper, etc.

●  The largest use of CMC is to prepare soap and synthetic detergents. About 1% of CMC is added to heavy-duty cleaners to prevent the washed out dirt from re-depositing on the fabric. Secondly, it is used as a suspension stabilizer for drilling mud in the petroleum industry. It can be used as an additive in the paper industry to improve the longitudinal strength and smoothness of paper. It can be used as a coating to improve the printing adaptability of paper. It is used as a thickener in the food industry. Emulsion stabilizer and ice crystal inhibitor of ice cream; in the textile industry, it can be used as a thickener for sizing agents and printing and dyeing pastes; in the pharmaceutical industry, it can be used as an emulsion stabilizer for injections, as a binder and film-forming agent for tablets; in the pharmaceutical industry It is used as a thickener in the production of cosmetics and ceramics. The toxicity test on CMC shows that oral and skin contact has no physiological activity at all, and no toxicity is found even if the dose of 10g/kg is taken orally by mice. The Food and Agriculture Organization of the United Nations and the World Health Organization Special Committee have also confirmed the safety of the product, and stipulated that the allowable daily intake (ADI) of human beings is 0-30mg/kg.

●  Polyanionic cellulose (Poly anioniccellulose), referred to as PAC, is a water-soluble cellulose ether derivative obtained by chemically modifying natural cellulose. It is an important water-soluble cellulose ether, and its sodium salt is usually used. Polyanionic cellulose has good heat resistance stability and salt resistance, and strong antibacterial properties. The mud fluid prepared by this product has good water loss reduction, inhibition and high temperature resistance. Widely used in oil drilling, especially salt water wells and offshore oil drilling. PAC-LV: low viscosity polyanionic cellulose.

Production method

●  The production method of carboxymethyl cellulose is to react cellulose with sodium hydroxide to form alkali cellulose, and then carry out carboxymethylation with monochloroacetic acid. The preparation method can be divided into the water-based method in which the reaction is carried out in water as the medium, and the solvent method in which the reaction is carried out in a solvent such as isopropanol, ethanol, or acetone.
Add refined cotton, caustic soda, alcohol mixture, and chloroacetic acid alcohol solution into the kneader for alkalization and etherification. Neutralize with hydrochloric acid, wash with alcohol, then dry and crush to obtain the product.

●  Immerse the degreased and bleached cotton thread in 35% concentrated lye solution in proportion, and take it out after soaking for about 30 minutes. Liquid caustic soda can be recycled. Weigh the soaked short cotton strands onto a flat press, press out the lye with a pressure of 14 MPa, and obtain alkalized cotton.
Put the alkalized cotton into the etherification kettle, add 15 parts of alcohol, slowly add the chloroacetic acid alcohol solution under stirring, complete at 30 °C for 2 h, and then stir at 40 °C for 3 h to obtain the etherified cotton. Add 120 parts of alcohol (70%) to etherified cotton, stir for 0.5 h, add hydrochloric acid to adjust the pH to 7. Wash twice with alcohol, filter out the alcohol, air-dry at 80°C, and pulverize to obtain the finished product.
According to different ingredient ratios, products with low degree of substitution (<0.4) and medium degree of substitution (0.4-1.2) can be produced.

●  Treat cellulose with sodium hydroxide to form alkali cellulose, mix with sodium monochloroacetate, and ripen for several days (20-30°C) to obtain the product

●  Usually, refined cotton is used as raw material, reacted with sodium hydroxide to form alkali cellulose, and then carboxymethylated with chloroacetic acid to obtain the finished product.
(C6H9O4OH)n+nNaOH→(C6H9O4ONa)n[ClCH2COOH]→(C6H9O4OCH2COONa)n
The techniques used in China include the traditional water-medium method using water as the medium and the solvent-based method using organic solvents as the reaction medium.
traditional water media
Spray 18%-19% lye into the kneader, alkalize the refined cotton at 30-35°C to form alkali cellulose, and then knead and etherify it with solid sodium chloroacetate. The temperature is controlled below 35°C for the first 1 to 2 hours; the temperature is controlled at 45 to 55°C for the next 1 hour. After a period of aging (to complete the etherification), it is dried and crushed to obtain the finished product.
solvent method
The refined cotton is put in the kneader, and the lye is sprayed into the kneader according to a certain flow rate to make the cellulose fully expanded. At the same time, an appropriate amount of ethanol is added, and the alkalization temperature is controlled at 30-40°C for 15-25 minutes. After alkalization is complete, spray into chloroacetic acid ethanol solution, and etherify at 50-60°C for 2 hours. Then use hydrochloric acid ethanol solution to neutralize and wash to remove sodium chloride, use a centrifuge to dealcoholize and remove water, and finally dry and pulverize to obtain the finished product.

Team Presentation