Palmitoylethanolamide CAS 544-31-0

CAS number：544-31-0
molecular formula：C18H37NO2
molecular weight：299.49
EINECS number：208-867-9

English synonyms

N-(2-HYDROXYETHYL)HEXADECANAMIDE;N-HEXADECANOYLETHANOLAMINE;PEA PALMIDROL;PALMITYLETHANOLAMIDE;PALMITOYLETHANOLAMIDE;PALMITOYLETHANOLAMIDE N-(2-HYDROXYETHYL)HEXADECANAMIDE;n-(2-hydroxyethyl)-hexadecanamid;Palmidrol

Related categories

Pharmaceutical raw materials;Synthesis;Biochemicals;Organic raw materials;Other raw materials;APIs;Main;Organic chemical raw materials;API APIs-Veterinary APIs;Large goods;Cannabinoid receptor;Cannabinoid;Products;APIs-API;Materials intermediates ;Standards;Amino compounds

Introduction

Hexadecanoethanol (PEA) is an endogenous fatty acid amide that belongs to the class of nuclear factor agonists. It has been shown to bind to receptors in the nucleus (nuclear receptors) and exert a large variety of biological functions associated with chronic pain and inflammation.

Chemical properties

Melting point	97-98℃
Boiling point	461.5±28.0 °C(Predicted)
Density	0.910±0.06 g/cm3(Predicted)
Vapor Pressure	0.45Pa at 20℃
RTECS	ML8950000
Storage conditions	-20°C
Solubility	Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
Shape	White solid
Acidity coefficient(pKa)	14.49±0.10(Predicted)
Color	White
Water solubility	4.01mg/L at 20℃
Stability	Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
InChIKey	HXYVTAGFYLMHSO-UHFFFAOYSA-N
LogP	3.989 at 20℃
CAS database	544-31-0

Use

● Hexadecylamide ethanol is an organic synthesis intermediate and a pharmaceutical intermediate, which can be used in the laboratory research and development process and the chemical and pharmaceutical research and development process.

● PEA has been shown to have anti-inflammatory, antinociceptive, neuroprotective, and anticonvulsant properties. PEA has been exploring various pain states in humans in different clinical trials for inflammation and pain syndromes.