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      Melatonine CAS 73-31-4

      • Melatonine CAS 73-31-4...
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      Detailed introduction



      CAS number:73-31-4
      molecular formula:C13H16N2O2
      molecular weight:232.28
      EINECS number:200-797-7

      English synonyms

      Melatonin (AS);Melatonine,N-(2-(5-Methoxyindol-3-yl)ethyl)acetaMide;MELATONINE FOR SYNTHESIS 1 G;MELATONINE FOR SYNTHESIS 5 G;Melatonin solution;N-[2-(5-METHOXY-1H-INDOL-3-YL)ETHYL]ACETAMIDE;N-(2-(5-methoxyindol-3-yl)ethyl)acetamide;MLT

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      Vitamins; pharmaceutical raw materials; synthetic materials; cosmetic raw materials whitening effect; health care products, medicine; nutrition research; intermediates; amino acids; heterocyclic series; medicine and biochemical industry; raw materials; nitrogen compounds; ;Plant extracts;Reference substances;Biochemical reagents;Pharmaceutical intermediates;Small molecule inhibitors;Small molecule inhibitors, natural products;Food additives;Amino acids;Chemical products-organic chemicals;Pharmaceutical raw materials;Plant biochemical extracts;Pharmaceutical raw materials ; Cosmetic raw materials - whitening agent; other biochemical reagents; pharmaceuticals; nutritional enhancers; organic raw materials; chemical raw materials; biochemical reagents - amino acids; medical raw materials; nutritional enhancers; daily chemical raw materials; reference substances - traditional Chinese medicine reference substances; ;Standards, reference substances;Raw materials;Pharmaceutical, pesticide and dye intermediates;Pesticide intermediates;Chemical raw materials-APIs;Melatonin;Chemical materials;Cosmetic raw materials;Chemical raw materials;Other chemical products;Daily chemicals;Comparison Listed products; technical intermediates; medical raw materials; other categories; antiviral intermediates; chemical reagents; chemical industry;
      Heterocyclic Series; Heterocycles series; Indoles; Tryptamines; Chemical Synthesis;Heterocyclic Building Blocks;M;Neurobiology;Neuroscience;Nutrition Research;Pharmacologicals;Phytochemicals by Chemical Classification;Vitamin series;Herb extract;Melatonex;inhibitor;Other APIs;Cosmetics;cosmetics materials;bulk drug material;general-purpose biochemical reagents;Inhibitors -amino acid; content product; raw material intermediate; kit-Elisa kit; 73-31-4; reference substance, active ingredient monomer; water retaining agent

      Introduction

      Melatonin is an indispensable natural hormone in the human body, which controls and affects the secretion of other different hormones. When melatonin in the body decreases, various functions of the human body will be affected, and various diseases will follow. Studies have shown that the secretion of melatonin in the human body begins to decrease after middle age, and its secretion is negligible in old age. Taking enough melatonin as early as possible can improve the function of the endocrine system, enhance immunity, improve anti-stress and anti-oxidation functions, improve sleep, slow down the aging speed of the human body, and slow down the degeneration of sexual organs; melatonin can also help prevent and treat cancer , It is especially helpful for habitual insomnia.

      Chemical properties

      Melting point

      116.5-118 °C (lit.)

      Boiling point

      374.44°C (rough estimate)

      Density

      1.1099 (rough estimate)

      Refractive index

      1.6450 (estimate)

      Flash point

      9℃

      Storage conditions

      -20°C

      Solubility 

      Soluble in ethanol to at least 50mg/ml

      Acidity coefficient(pKa)

      16.26±0.46(Predicted)

      Shape

      Powder

      Color

      white to off-white

      Merck 

      14,5816

      BRN 

      205542

      InChIKey

      DRLFMBDRBRZALE-UHFFFAOYSA-N

      CAS database

      73-31-4(CAS DataBase Reference)

       Use

      ●  Used in medicine and health products, it can enhance the immune function of the human body, prevent aging and restore youth, and is a natural "sleeping pill".

      ●  It is a hormone secreted by the pineal body of the pituitary gland in the body. The amount of this hormone secreted is related to the light. The weaker the light, the more the secretion, and vice versa, the less it helps sleep.

      ●  biochemical research

      ●  Melatonin has complex effects on apoptotic pathways, inhibiting apoptosis in immune cells and neurons but enhancing apoptotic cell death of cancer cells. Inhibits proliferation/metastasis of breast cancer cells by inhibiting estrogen receptor action.

      ●  Used in medicine and health products, it can enhance the immune function of the human body and is a natural "sleeping pill"

      Production method

      ●  Melatonin exists in the pineal gland of the mammalian brain. The general method is to freeze-dry the pineal gland of the bovine brain, grind it into powder, remove the fat with petroleum ether, mix it with deionized water to form a slurry, and perform centrifugation Finally, the supernatant was taken, extracted with an equal volume of ethyl acetate, and the extract was vacuum-dried to obtain a crude product of white melatonin, which was then recrystallized to obtain a refined product.

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