Chlorphenesin CAS 104-29-0
CAS number：104-29-0
molecular formula：C9H11ClO3
molecular weight：202.63
EINECS number：203-192-6
English synonyms
3-(4-CHLOROPHENOXY)-1,2-PROPANEDIOL;GLYCEROL A-P-CHLOROPHENYL ETHER;LABOTEST-BB LT01147791;CHLORPHENESIN;CHLORPHENESINE;CHLORPHENSIN;3-(PARA-CHLOROPHENOXY)-1,2-PROPANEDIOL;Chlorophenesin (CHP)
Related categories
Organic chemical industry; pharmaceutical raw materials; synthesis; food and feed additives; agricultural raw materials; benzene; chemical industry; chemical raw materials; raw materials; standard products; cosmetic raw materials; organic chemical raw materials; raw materials; cosmetic raw materials-functional raw materials; ;Cosmetic additives; Auxiliaries; Chemical intermediates; Antibacterial and antiseptic; Chemical raw materials-1827181813; chemical products; antibacterial and antiseptic; cosmetic raw materials; cosmetics; daily chemical raw materials; cosmetic additives; ;Bactericidal preservatives;Chemical products-organic chemicals;Chemical products;Chemical reagents;Organic raw materials
Introduction
Chlorphenesin is a preservative widely used in cosmetics and is compatible with most preservatives (including potassium sorbate, sodium benzoate, methylisothiazolinone). It appears as white crystals, usually with a weak characteristic odor. The melting point is 77.0-80.5°C. Slightly soluble in water (about 0.5%). The solubility in 95% ethanol is 5%. Soluble in ethers. Slightly soluble in fixed oil, insoluble in white mineral oil. Microbial control performance: can provide improved broad-spectrum antibacterial activity. It has the ability to inhibit and kill G+, G-, Aspergillus niger, Penicillium pinophilum, Candida albicans and Saccharomyces cerevisiae.
Chemical properties
| Melting point | 77-79°C |
| Boiling point | 290.96°C (rough estimate) |
Density | 1.2411 (rough estimate) |
| Vapor Pressure | 0Pa at 25℃ |
| Refractive index | 1.5470 (estimate) |
RTECS | TY4260000 |
Storage conditions | Sealed in dry,Room Temperature |
Solubility | DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly, Sonicated) |
| Shape | Solid |
| Acidity coefficient(pKa) | 13.44±0.20(Predicted) |
| Color | White to Off-White |
| Water solubility | Slightly soluble in water. |
LogP | 1.23 at 23℃ |
| CAS database | 104-29-0(CAS DataBase Reference) |
Use
● Chlorphenesin is more effective against fungi, and when used in combination with other preservatives, the antiseptic effect is enhanced.
● Chlorphenesin is a preservative widely used in cosmetics. It has been allowed to be used as a preservative in cosmetics in Europe since 1996, and it is also allowed in Japan and the United States.
