Tris(2-carboxyethyl)phosphine Hydrochloride (TCEP·HCl) | CAS 51805-45-9

Product Name: Tris(2-carboxyethyl)phosphine Hydrochloride

CAS Number: 51805-45-9

Molecular Formula: C₉H₁₆ClO₆P

Product Category: Biochemical Reagents / Protein Reducing Agents / Fine Chemicals

Product Overview

Tris(2-carbonylethyl)phosphohydrochloride (TCEP·HCl, CAS 51805-45-9) is a highly efficient and stable sulfur bond reducing agent, widely used in protein chemistry, biopharmaceuticals, molecular biology, and biochemical experiments.

Compared to traditional reducing agents (such as DTT and β-mercaptoethanol), TCEP has significant advantages such as low odor, high stability, absence of thiol groups, and resistance to oxidation by air.

This product is stable in aqueous solution for extended periods and is suitable for protein denaturation, renaturation, enzyme activity studies, and biopharmaceutical production. It is one of the commonly used reducing reagents in biological laboratories and the biopharmaceutical industry.

Technical Data Sheet

Main Application Areas

1️⃣ Protein and Biochemistry Research

Protein disulfide bond reduction

SDS-PAGE sample preparation

Protein structure and function research

2️⃣ Biopharmaceuticals and Diagnostic Reagents

Recombinant protein production

Antibody preparation and modification

In vitro diagnostic reagent development

3️⃣ Molecular Biology Experiments

DNA/RNA related experimental aids

Enzyme reaction system stabilizers

4️⃣ Scientific and Industrial Biological Applications

Raw materials for biological reagent kits

Routine laboratory reducing reagents

Product Advantages

✔ Highly efficient disulfide bond reduction with rapid reaction

✔ Mercapto-free and odorless

✔ High water solubility and easy to use

✔ Stable in air and resistant to oxidation

✔ High purity, suitable for biopharmaceutical applications

Company and Supply Advantages (Why Choose Us)

🔹 Long-term supply of biochemical and fine chemicals

🔹 Strict quality control, stable batches

🔹 Provides COA/MSDS/TDS

🔹 Supports laboratory and industrial-grade procurement

🔹 Professional international logistics, global delivery

Packaging & Storage

 FAQ – Frequently Asked Questions 

Q1: What is TCEP hydrochloride mainly used for?
A: It is mainly used as a reducing agent for disulfide bonds in proteins.

Q2: How does TCEP compare with DTT?
A: TCEP is more stable, odorless, and does not oxidize easily in air.

Q3: Is this product water soluble?
A: Yes, it is highly soluble in water.

Q4: Can it be used in biological systems?
A: Yes, it is widely used in biochemistry and biopharmaceutical applications.

Q5: Do you supply bulk quantities?
A: Yes, laboratory and industrial-scale supply are both available.