Green Coffee Bean Extract Chlorogenic acid CAS 327-97-9
Green coffee bean extract is derived from unroasted coffee beans. The core active ingredient is chlorogenic acid, which has significant antioxidant, sugar control and fat-reducing effects.
Active ingredients and efficacy verification
| Element | Content range | Core Benefits | Clinical evidence |
| Chlorogenic acid | 10%-98% (HPLC) | Inhibit glucose absorption and promote fat metabolism | Daily intake of 300 mg resulted in a weight loss of 5.7 kg in 8 weeks (JISSN 2021) |
| caffeine | ≤2% | Increase metabolic rate and enhance exercise endurance | Exercise can increase fat burning efficiency by 30% |
Mechanism of action:
Weight management: Blocks α-glucosidase and reduces the conversion of carbohydrates into fat;
Antioxidant: ORAC value is twice that of green tea, neutralizing free radical damage;
Blood sugar regulation: Reduces postprandial blood sugar peak by 20% and improves insulin sensitivity.
Extraction process and quality control
Traditional process: ethanol reflux extraction, yield 12%-15%, high risk of solvent residue;
Innovative technology:
Supercritical CO₂ extraction: chlorogenic acid purity increased to 98%, no solvent residue;
Nano-encapsulation technology: bioavailability increased by 3 times, suitable for functional beverages.
Safety indicators: heavy metals (Pb≤0.5ppm), pesticide residues (＜2ppm), in compliance with FDA 21 CFR 172.510.
Application Scenario
1. Functional foods and supplements
| Category | Recipe | Market Case |
| Weight Management Coffee | Chlorogenic acid ≥430mg/strip + L-carnitine | Chongshangran Coffee (monthly sales on Tmall: 100,000+, repurchase rate: 85%) |
| Meal Replacement Powder | Compound White Kidney Bean Extract (Starch Blocking) | Swanson Capsules (iHerb Category TOP6) |
| Sports Nutrition Drinks | Added BCAA + 5g Creatine | Improve endurance by 59% and reduce oxidative damage after exercise |
2. Cosmeceuticals and medicine
Anti-aging essence: 1% chlorogenic acid inhibits collagen degradation and improves wrinkles by 28% in 8 weeks;
Antihypertensive drugs: Clinical trials show that systolic blood pressure is reduced by an average of 5-7 mmHg.
Technical parameters and certification
| Index | Parameter Value | Testing standards |
| Active ingredients | Chlorogenic acid 10%-50% (HPLC) | USP 43 |
| CAS Number | 327-97-9 | Blood pressure lowering, anti-tumor, kidney tonifying, anti-oxidation |
| Appearance | Light yellow to brown powder | EP 10.0 |
| Solubility | Water soluble (1% solution transmittance ≥ 90%) | ICH Q3C |
| Heavy metal residues | Pb≤0.5ppm, As≤0.3ppm | ICP-MS |
| Microbiological Control | Total colony count <1000 CFU/g, no pathogenic bacteria | ISO 4833-1:2013 |
Supply chain and procurement advantages
Raw material traceability: Yunnan organic coffee beans (soil heavy metal test report can be traced)
Packaging specifications:
1kg aluminum foil bag (nitrogen filled to prevent moisture)
25kg cardboard barrel (lined with PE film)
Inventory and timeliness:
Spot: 50% chlorogenic acid powder inventory 1.2 tons (5 working days global delivery)
Customization: Support 10kg minimum order (70% high purity), production cycle 2 weeks
Cost optimization:
Annual purchase > 500kg enjoys tiered price (50% content $150/kg → $135/kg)
