High Purity Mangosteen Extract (40%-90% α-Mangostin) Supplier | Antioxidant/Anti-Inflammatory/Anti-Aging Raw Materials | CAS 90045-25-3
——————
CAS number ： 90045-25-3
molecular formula : 0
EINECS ： 0
——————
Email ： info@deshangchem.com
Mobile : 8613153039501
TEL ： +86-531-88752665
Mangosteen extract uses the peel of the "Queen of Fruits" Garcinia mangostana as its core raw material. It is rich in xanthones, especially the star ingredient α-Mangostin (CAS 6147-11-1), which has an antioxidant capacity more than 20 times that of vitamin C. It has become a popular raw material in the global anti-aging, anti-inflammatory and metabolic health fields.
1. Active ingredients and efficacy verification
| Element | Content range | Core Benefits | Clinical evidence |
| α-Mangostin | 10%-95% (HPLC) | Anti-inflammatory, antibacterial, inducing cancer cell apoptosis | Inhibits HL60 leukemia cells (10 μmol concentration is effective) |
| γ-Mangostin | 5%-8% | Blocks prostaglandin synthesis and reduces joint swelling | The inhibition rate of rat carrageenan edema model is ＞50% |
| Polyphenols (OPCs) | ≥20% | Synergistic antioxidant effect to reduce blood sugar fluctuations | Diabetic patients take 200 mg per day, and the systolic blood pressure drops by 5-7 mmHg |
Mechanism of action:
Anti-inflammatory targets: inhibit COX-2 activity and NO synthesis, reduce inflammatory factors such as IL-1β and TNF-α.
Antibacterial spectrum: The inhibition rate of drug-resistant Staphylococcus aureus (MRSA) and Propionibacterium acnes is >90%.
2. Innovation of extraction process
Traditional process: 95% ethanol refluxed 3 times, yield 12%-15%, high cost and residual risk.
Patented technology (CN116139191A):
Formic acid-ethanol step extraction: α-mangostin extraction rate increased by 40%.
Microwave-ultrasound synergy: energy consumption reduced by 30%, production cycle shortened to 4 hours.
Green certification: in compliance with ISO 22000, KOSHER, solvent residue <50ppm (GC method).
Product Technical Parameters
| Index | Parameter Value | Testing standards |
| Active ingredients | α-Mangostin 40%-90% (HPLC) | USP 43 |
| Appearance | Light yellow to brown powder | EP 10.0 |
| Solubility | Lipid soluble (ethanol/chloroform) | ICH Q3C |
| Heavy metal residues | Pb≤0.5ppm, As≤0.3ppm | ICP-MS |
| Microorganism | Total colony count <1000 CFU/g, no pathogenic bacteria | ISO 4833-1:2013 |
Application scenarios and hot product solutions
1. Functional food development
Hangover and liver protection soft candy: 200mg mangosteen extract + 100mg curcumin, clinically reduced ALT/AST 30%-40% in 6 weeks
Sports recovery drink: compound BCAA, reduce post-exercise oxidative damage (MDA level ↓40%)
2. Cosmeceutical anti-aging hot products
Anti-acne essence: 1% α-mangostin + tea tree oil, 48-hour Propionibacterium acnes inactivation rate 99%
Anti-wrinkle cream: 3% nano-encapsulated mangosteen extract, 8 weeks to improve wrinkle depth 28% (ultraviolet-induced collagen degradation inhibition)
3. Medical-grade solutions
Japanese functional food: 18mg/day garcinia alcohol (derived from mangosteen), approved to claim "relieve fatigue when getting up + liver function maintenance"
Supply chain advantages and procurement policies
Packing specifications: 1kg aluminum foil bag (nitrogen filled to prevent oxidation)/25kg cardboard barrel (lined with PE film)
Inventory and delivery time:
Spot: 40% α-mangostin (1.2 tons in stock), 5 working days for global delivery
Customization: 90% high purity (supports 10kg minimum order), production cycle 2-3 weeks
High Purity Mangosteen Extract (40%-90% α-Mangostin) Supplier | Antioxidant/Anti-Inflammatory/Anti-Aging Raw Materials | CAS 90045-25-3
Mangosteen extract uses the peel of the "Queen of Fruits" Garcinia mangostana as its core raw material. It is rich in xanthones, especially the star ingredient α-Mangostin (CAS 6147-11-1), which has an antioxidant capacity more than 20 times that of vitamin C. It has become a popular raw material in the global anti-aging, anti-inflammatory and metabolic health fields.
1. Active ingredients and efficacy verification
| Element | Content range | Core Benefits | Clinical evidence |
| α-Mangostin | 10%-95% (HPLC) | Anti-inflammatory, antibacterial, inducing cancer cell apoptosis | Inhibits HL60 leukemia cells (10 μmol concentration is effective) |
| γ-Mangostin | 5%-8% | Blocks prostaglandin synthesis and reduces joint swelling | The inhibition rate of rat carrageenan edema model is ＞50% |
| Polyphenols (OPCs) | ≥20% | Synergistic antioxidant effect to reduce blood sugar fluctuations | Diabetic patients take 200 mg per day, and the systolic blood pressure drops by 5-7 mmHg |
Mechanism of action:
Anti-inflammatory targets: inhibit COX-2 activity and NO synthesis, reduce inflammatory factors such as IL-1β and TNF-α.
Antibacterial spectrum: The inhibition rate of drug-resistant Staphylococcus aureus (MRSA) and Propionibacterium acnes is >90%.
2. Innovation of extraction process
Traditional process: 95% ethanol refluxed 3 times, yield 12%-15%, high cost and residual risk.
Patented technology (CN116139191A):
Formic acid-ethanol step extraction: α-mangostin extraction rate increased by 40%.
Microwave-ultrasound synergy: energy consumption reduced by 30%, production cycle shortened to 4 hours.
Green certification: in compliance with ISO 22000, KOSHER, solvent residue <50ppm (GC method).
Product Technical Parameters
| Index | Parameter Value | Testing standards |
| Active ingredients | α-Mangostin 40%-90% (HPLC) | USP 43 |
| Appearance | Light yellow to brown powder | EP 10.0 |
| Solubility | Lipid soluble (ethanol/chloroform) | ICH Q3C |
| Heavy metal residues | Pb≤0.5ppm, As≤0.3ppm | ICP-MS |
| Microorganism | Total colony count <1000 CFU/g, no pathogenic bacteria | ISO 4833-1:2013 |
Application scenarios and hot product solutions
1. Functional food development
Hangover and liver protection soft candy: 200mg mangosteen extract + 100mg curcumin, clinically reduced ALT/AST 30%-40% in 6 weeks
Sports recovery drink: compound BCAA, reduce post-exercise oxidative damage (MDA level ↓40%)
2. Cosmeceutical anti-aging hot products
Anti-acne essence: 1% α-mangostin + tea tree oil, 48-hour Propionibacterium acnes inactivation rate 99%
Anti-wrinkle cream: 3% nano-encapsulated mangosteen extract, 8 weeks to improve wrinkle depth 28% (ultraviolet-induced collagen degradation inhibition)
3. Medical-grade solutions
Japanese functional food: 18mg/day garcinia alcohol (derived from mangosteen), approved to claim "relieve fatigue when getting up + liver function maintenance"
Supply chain advantages and procurement policies
Packing specifications: 1kg aluminum foil bag (nitrogen filled to prevent oxidation)/25kg cardboard barrel (lined with PE film)
Inventory and delivery time:
Spot: 40% α-mangostin (1.2 tons in stock), 5 working days for global delivery
Customization: 90% high purity (supports 10kg minimum order), production cycle 2-3 weeks
Team Presentation
Firm：Shandong Deshang Chemical Co., LTD
Phone
：+8613153039501
Email
：info@deshangchem.com
Add：11th Floor, Chuangbo Industrial Park, 177 Tianchen Road, High-tech Zone, Jinan City, Shandong Province, China
Linke： worldsunchem chemechemi Benzoflex 9-88