Molecular Formula: C₆₄H₁₄O₂₆
Molecular Weight: 1310 g/mol
Other Names: Tween 80, Polyoxyethylene sorbitan monooleate, Polysorbate-80
Polysorbate 80 (CAS 9005-65-6) is a nonionic surfactant produced by the reaction of sorbitol and ethylene oxide. It appears as a yellow to amber viscous liquid. It exhibits excellent emulsifying, dispersing, and solubilizing properties and is widely used in food, cosmetics, pharmaceutical preparations, agricultural adjuvants, and industrial emulsification systems. It is commonly used as an emulsifier, solubilizer, and stabilizer in pharmaceuticals and as an additive (E433) in foods.
Tween 20 is a surfactant, a clear, yellow or amber oily liquid with a distinctive odor and a slightly bitter taste. It is commonly used as a stabilizer in the production process or final formulation of biological products. It is produced by the reaction of sorbitan monolaurate with ethylene oxide.
Appears as an amber-colored, viscous liquid with a slight, distinctive odor and a slightly bitter taste. Relative density is 1.08-1.13, and the boiling point is 321°C. It is soluble in water, ethanol, methanol, and ethyl acetate, but insoluble in mineral oil and petroleum ether. Its HLB value is 16.7. The oral LD50 in rats is 37 g/kg, and the Ad1 is 0-25 mg/kg (FAO/WHO, 1994). Tween 20 is a nonionic surfactant.
Property | Specification |
---|---|
Product Name | Polysorbate 80 (Tween 80) |
CAS Number | 9005-65-6 |
Molecular Formula | C64H124O26 |
Molecular Weight | ~1310 g/mol |
Appearance | Yellow to amber viscous liquid |
Purity (HLB Value) | HLB ~15 |
Acid Value | ≤ 2.0 mgKOH/g |
Saponification Value | 45 – 55 |
Hydroxyl Value | 65 – 80 |
Density (25 °C) | 1.06 g/cm³ |
Solubility | Soluble in water, ethanol, methanol |
Shelf Life | 24 months |
Food Industry: As an emulsifier and stabilizer (food additive E433)
Pharmaceuticals: As a solubilizer and emulsifier in injections, oral solutions, and creams
Cosmetics and Personal Care: In skin care lotions, shampoos, sunscreens, and makeup removers
Agrochemicals: As an emulsifier for pesticides to improve their dispersion
Industrial Applications: In coatings, textile auxiliaries, and oilfield chemicals
✅ High purity and pharmacopoeia-grade quality (USP/NF, EP, JP)
✅ Excellent emulsification and solubilization properties
✅ Wide range of applications, including food, pharmaceuticals, and cosmetics
✅ Factory direct, supporting both small and large industrial packaging
✅ Complete documentation support: COA, MSDS, TDS
🌐 Over 15 years of experience in exporting surfactants and pharmaceutical excipients
🏆 Products certified by ISO, GMP, Halal, and Kosher
🚢 Global supply, ample inventory, and fast delivery
📑 Custom packaging and technical support available
Packaging: 200kg/iron drum; 20kg/drum
Storage: Sealed, stored in a cool, dry place away from light
Shelf Life: 24 months
Q1: Is Polysorbate 80 safe for food applications?
👉 Yes, Polysorbate 80 is approved as food additive E433 by FDA and EFSA.
Q2: Can it be used in pharmaceuticals?
👉 Yes, it is widely used as solubilizer and emulsifier in injections, oral solutions, and creams.
Q3: What certifications do you offer?
👉 We provide COA, MSDS, TDS and can supply Halal, Kosher, USP/NF, EP certificates.
Q4: Is it soluble in water?
👉 Yes, Polysorbate 80 is completely soluble in water and ethanol.
Q5: Can you supply pharma-grade Polysorbate 80?
👉 Yes, we supply both industrial grade and pharma-grade (USP/NF compliant).
📞Contact us for samples or a quote
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