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      Osthole CAS 484-12-8

      • Osthole CAS 484-12-8...
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      Detailed introduction



      CAS number:484-12-8
      molecular formula:C15H16O3
      molecular weight:244.29
      EINECS number:1532714-185-1

      English synonyms

      OSTHOL;OSTHOLE;AKOS 236-34;Chuanxiongzine;Cnidium lactone(OSTHOLE );7-methoxy-8-(3-methyl-2-butenyl)-coumari;7-Methoxy-8-(3-methyl-2-butenyl)-coumarin;7-Methoxy-8-isopentenylcoumarin

      Related categories

      Chinese herbal medicine ingredients; natural products; plant extracts; pharmaceutical raw materials; plant extracts; reference substances, standard substances; analytical standards; Chinese medicine reference substances; standard substances; cell biology reagents; reference substances; small molecule inhibitors; small molecule inhibitors , natural products; plant biochemical extracts; standard Chinese medicine; food additive raw materials; high-purity plant extracts; daily chemical raw materials; plant component monomers; biochemical reagents - other chemical reagents; ;raw materials;standards-standards of traditional Chinese medicine;proportion products;lignans;standards-standards of traditional Chinese medicines;analytical reagents-standards;chemical intermediates industrial raw materials;Standard extract;Natural Plant Extract;Steroids;Plant extract;Herb extract;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;natural product;Inhibitors;standards, reference substances;plant extract monomers;medicines, pesticides and dye intermediates; Cosmetic raw materials; biological reagents; proportional extracts; organic chemical raw materials; food additives; health care;

      Introduction

      Osthole is a substance extracted from the fruit of the annual herb Cnidium of the Umbelliferae, the appearance is yellow-green to white crystalline powder, insoluble in water and cold petroleum ether, easily soluble in acetone, methanol, ethanol, chloroform , chloroform, ethyl acetate, soluble in boiling petroleum ether, with antispasmodic, hypotensive, antiarrhythmic, immune enhancement and broad-spectrum antibacterial effects. Clinically, it is mainly used to treat male impotence, scrotal itching, vaginal itching in women, cold uterus, infertility, rheumatic arthralgia, scabies, eczema, and trichomonas vaginitis. Osthole can also be used as field insecticides and fungicides, mainly for contact killing, supplemented by stomach poisoning. It will eventually fail and die, and it has a good contact killing effect on a variety of pests such as cabbage worm, tea inchworm, cotton bollworm, beet armyworm and various aphids.

      Chemical properties

      Melting point

      83-84°C

      Boiling point

      347.2°C (rough estimate)

      Density

      1.1263 (rough estimate)

      Refractive index

      1.5570 (estimate)

      Storage conditions

      Sealed in dry,2-8°C

      Solubility

      methanol: soluble10mg/mL, clear, colorless

      Shape

      powder

      Color

      white

      Water solubility

      12mg/L(25 ºC)

      Maximum wavelength(λmax)

      322nm(MeOH)(lit.)

      Merck 

      14,6895

      InChIKey

      MBRLOUHOWLUMFF-UHFFFAOYSA-N

      CAS database

      484-12-8(CAS DataBase Reference)

      Soluble in alkaline solution, methanol, ethanol, chloroform, acetone, ethyl acetate and boiling petroleum ether, etc., insoluble in water and petroleum ether. From Umbelliferae Cnidium monnieric (L.) Cuss. the fruit 

      Use

      ●  It has antispasmodic, antihypertensive, antiarrhythmic, enhanced immune function and broad-spectrum antibacterial effects.

      ●  The active ingredients of Cnidium,



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