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      Parthenolide CAS 20554-84-1

      • Parthenolide CAS 20554-84-1...
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      Detailed introduction



      CAS number:20554-84-1
      molecular formula:C15H20O3
      molecular weight:248.32
      EINECS number:692-532-0

      English synonyms

      Parthenolide, Tanacetum parthenium - CAS 20554-84-1 - Calbiochem;Factory Price Parthenolide 20554-84-1;Natural Plant Extracts Parthenolide 20554-84-1 High Purity HPLC>98%;Feverfew P.E Parthenlide;[1aR-(1aR*,4E,7aS*,10aS*,-10bR*)]-2,3-6,7,7a,8,10a,10b-Octahydro-1a,5-dimethyl-8-methyleneoxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one;(1aR,4E,7aS,10aS,10bS)-2,3,6,7,7a,8,10a,10b-Octahydro-1a,5-dimethyl-8-methyleneoxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one;4,5α-Epoxy-6β-hydroxygermacra-1(10),11(13)-dien-12-oic acid γ-lactone;4,5alpha-epoxy-6beta-hydroxy-germacra-1(10),11(13)-dien-12-oic acid gamma-lactone

      Related categories

      Analytical standard substance; Chinese medicine reference substance; standard substance; Chinese medicine standard substance; pharmaceutical raw material; plant extract; reference substance; other raw materials; standard substance - Chinese medicine standard substance; other biochemical reagents;
      Sesqui-Terpenoids;Isoprenoid/terpenoidNeurotransmitters;Anti-Proliferative AgentsNutrition Research;Antitumor Agents;Natural Product;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;inhibitor;
      Advantage product;Analytical reference substance;Standard extract;Standard product-Chinese medicine standard product;Sesquiterpene;Standard extract;Analytical reagent standard product;Natural high content monomer;High content monomer;Biochemicals Found in Plants;Cancer Research; Others;Serotonergics;Prostanoid receptor and related

      Introduction

      Parthenolide is a natural product of sesquiterpene lactones, isolated from medicinal plants such as tansy and eucalyptus, which are widely used in fever, deworming and anti-inflammatory. In recent years, studies have confirmed that parthenolide has a variety of important pharmacological activities, such as anti-tumor, anti-viral, anti-inflammatory and anti-atherosclerosis. Rheumatoid Arthritis etc.

      Melting point

      115-116 °C (lit.)

      Boiling point

      394.1±42.0 °C(Predicted)

      Specific optical rotation

      D20 -81.4° (c = 1.04 in chloroform); D22 -71.4° (c = 0.220 in CH2Cl2)

      Density

      1.13±0.1 g/cm3(Predicted)

      Storage conditions

      -20°C

      Solubility

      Soluble in DMSO (up to 100 mg/ml) or in Ethanol (up to 20 mg/ml)

      Shape

      White solid

      Color

      White

      Merck 

      14,7048

      Stability

      Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.

      CAS database

      20554-84-1

      ●  The sesquiterpene lactone compound parthenolide is a compound extracted from parthenolide that was originally used to treat skin infections, rheumatism, and migraines. Recent studies have shown that parthenolide can inhibit the growth of prostate cancer, breast cancer, gastric cancer, leukemia cancer, kidney cancer, lung cancer, colon adenocarcinoma, medulloblastoma and other cancer cells. It can treat skin cancer caused by ultraviolet rays.

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