CAS number：117-39-5
molecular formula：C15H10O7
molecular weight：302.24
EINECS number：204-187-1

English synonyms

3,3',4',5,7-Pentahydroxyflavone 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one;MELETIN;FLAVIN MELETIN;LABOTEST-BB LT00455149;CI NO 75670;XANTHAURINE;QUERCETINE;QUERTINE

Related categories

Pharmaceutical raw materials; Chinese medicine standard products; small molecule inhibitors, natural products; plant biochemical extracts; reference substances; cardiovascular; pharmaceutical intermediates; plant extracts; antioxidants; food additives; raw materials; traditional Chinese medicine reference substances; standard substances; Reference substance, standard substance; analytical standard substance; small molecule inhibitor; phytochemical drug; standard plant extract; analytical reference substance; reagent; standard substance-control substance; chemical industry; plant extraction; cell biology reagent;
Pharmaceutical Raw Materials;Miscellaneous Natural Products;Functional Products;Natural Plant Extract;Caspases/Apoptosis;reference substance;Plant extracts;Herb extract;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese. ;natural product;Inhibitors;TROXEPURE;
Medical raw materials; standard substances, reference substances; standard substances - traditional Chinese medicine standard substances; extracts; flavonoids; standard substances - traditional Chinese medicine standard substances; in vitro research products - in vitro metabolism standard substances; other raw materials; ;Plant Component Monomer;Sophora japonica series;Plant Extract;Jiahe;Chemical Reagent;plant extract

Introduction

Quercetin is an expectorant drug commonly used in clinical practice of traditional Chinese medicine in my country. This product has good expectorant and cough-relieving effects, and also has a certain anti-asthma effect. It can also lower blood pressure, improve capillary resistance, and reduce capillary Pharmacological functions of fragility, lowering blood fat, dilating coronary arteries, and increasing coronary blood flow.
Clinical quercetin is mainly used for bronchitis and phlegm inflammation. It also has an adjuvant therapeutic effect on patients with coronary heart disease and hypertension. Using this product may cause dry mouth, dizziness and burning sensation in the stomach area, which will disappear after stopping the drug.
Quercetin is widely found in angiosperms, such as red pipe medicine, cat's eye grass, iron-clad gold, mansanhong, loquat loquat, azalea, zhaoshanbai, low ground tea, and apocynum. It is a glycoside This kind of aglycone often exists in the form of glycosides combined with sugar, such as quercetin, rutin, hyperin, etc.

Chemical properties

Yellow needle-like crystalline powder. Stable to heat, the decomposition temperature is 314°C. It can improve the light fastness of the pigment in the food and prevent the change of the flavor of the food. It will change color in case of metal ions. Slightly soluble in water, easily soluble in alkaline aqueous solution. Quercetin and its derivatives are a class of flavonoids widely present in various vegetables and fruits. Such as onion, seabuckthorn, hawthorn, locust tree, tea and so on. It has anti-free radical, anti-oxidation, anti-bacterial, anti-viral, anti-allergic effects. When used in lard, etc., various antioxidant indicators are similar to BHA or PG.

Use

●  Antioxidants. Mainly used in oil, beverage, cold drink, meat processing products.

●  It has good effects of eliminating phlegm, relieving cough and relieving asthma. It is used to treat chronic bronchitis, and also has auxiliary therapeutic effect on patients with coronary heart disease and hypertension.

●  Analytical Standards

●  A flavonoid compound with anti-cancer activity, is a mitochondrial ATPase and phosphodiesterase inhibitor, inhibits PI3 kinase activity and slightly inhibits PIP kinase activity, IC50: 3.8μM. Has anti-proliferative effects on cancer cell lines, reduces cancer cell growth through type II estrogen receptors, and arrests human leukemia T cells in the late G1 phase of the cell cycle. Inhibits fatty acid synthase activity.

Production method

●  Grind the bark of the Quercus plant of the Fagaceae into powder, wash it with hot salt water, extract it with dilute ammonia water, and neutralize it with dilute sulfuric acid. Boiling the filtrate, resulting in crystallization.
It can be extracted with 95% ethanol from Liliaceae plant onion (Alliumcepa); it can also be extracted from rutin (rutin) extract and quercetin, isoquercitrin, anisin, hyperin, quercetin, lasume glycoside, etc. It can be obtained by hydrolysis with rutin decomposing enzyme or acidic aqueous solution.

Team Presentation